Toxtree publications

If you use Toxtree, please cite the following paper:

• Patlewicz G, Jeliazkova N, Safford RJ, Worth AP, Aleksiev B. (2008) An evaluation of the implementation of the Cramer classification scheme in the Toxtree software. SAR QSAR Environ Res. ;19(5-6):495-524.

or/and these web sites:

• JRC Computational Toxicology

• Toxtree site

For publications, specific to plugins, refer to the plugin page and manuals.

• Revised Cramer Decision Tree NEW!

• Cramer rules and Cramer rules with extensions

• Verhaar scheme and Modified Verhaar scheme

• Skin irritation prediction

• Eye irritation prediction

• START biodegradation and persistence

• Benigni / Bossa rulebase for mutagenicity and carcinogenicity

• In vitro mutagenicity (Ames test) alerts by ISS

• Structure Alerts for the in vivo micronucleus assay in rodents (ISSMIC)

• Structural Alerts for Functional Group Identification (ISSFUNC)

• Structure Alerts for identification of Michael Acceptors

• Structure Alerts for skin sensitisation reactivity domains

• DNA binding alerts

• Protein binding alerts

• Kroes TTC Decision tree

• SMARTCyp - Cytochrome P450-Mediated Drug Metabolism and metabolites prediction

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