Toxtree – Toxtree Module: In vitro mutagenicity (Ames test) alerts by ISS

A decision tree for estimating in vitro mutagenicity (Ames test).

Available since ToxTree 2.6.0

Developed by Istituto Superiore di Sanita for the EC Joint Research Centre, Computational Toxicology and IdeaConsult Ltd. Sofia, Bulgaria

Screenshots: Main screen , Decision tree

Reference

Benigni, R. & Bossa, C. (2011). Mechanisms of chemical carcinogenicity and mutagenicity: a review with implications for predictive toxicology. Chem. Revs. 111, 2507-2536.
Benigni, R., Bossa C., Tcheremenskaia O. (2013) In vitro cell transformation assays for an integrated, alternative assessment of carcinogenicity: a data-based analysis. Mutagenesis 2013;28(1):107-16.

For developers

<dependency>
  <groupId>toxtree</groupId>
  <artifactId>toxtree-ames</artifactId>
  <version>3.1.0</version>
</dependency>

Repository

<repository>
        <id>ambit-releases</id>
        <url>https://nexus.ideaconsult.net/content/repositories/releases</url>
   </repository>